Searched for:  hsa-mir-181d

hsa-mir-181d mutations modulate:

List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Mutations in hsa-mir-181d are not predicted modulate anything in gbmSYGNAL.
 

hsa-mir-181d regulates:

List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
RegulatorRegulated Biclusters
hsa-mir-181d15
Regulator (Action)BiclusterSurvival (p-value)Hallmark(s)
hsa-mir-181d (Rep.)PITA_4383.48 (5.0E-04)
hsa-mir-181d (Rep.)PITA_763.19 (1.4E-03)Tumor promoting inflammationEvading immune detection
hsa-mir-181d (Rep.)PITA_1222.57 (1.0E-02)
hsa-mir-181d (Rep.)PITA_5162.62 (8.9E-03)Tumor promoting inflammationEvading immune detection
hsa-mir-181d (Rep.)TARGETSCAN_503.80 (1.4E-04)
hsa-mir-181d (Rep.)TARGETSCAN_1512.60 (9.4E-03)
hsa-mir-181d (Rep.)TARGETSCAN_4873.39 (6.9E-04)
hsa-mir-181d (Rep.)TARGETSCAN_5334.20 (2.6E-05)
hsa-mir-181d (Rep.)TARGETSCAN_5622.77 (5.6E-03)Tumor promoting inflammationEvading immune detection
hsa-mir-181d (Rep.)TARGETSCAN_5923.17 (1.5E-03)
hsa-mir-181d (Rep.)TFBS_DB_512.51 (1.2E-02)
hsa-mir-181d (Rep.)TFBS_DB_1253.99 (6.7E-05)
hsa-mir-181d (Rep.)TFBS_DB_4282.62 (8.9E-03)Tumor promoting inflammationSelf sufficiency in growth signalsEvading immune detectionInsensitivity to antigrowth signals
hsa-mir-181d (Rep.)PITA_2623.22 (1.3E-03)
hsa-mir-181d (Rep.)PITA_2623.22 (1.3E-03)
hsa-mir-181d (Rep.)TARGETSCAN_383.19 (1.4E-03)

Biclusters containing hsa-mir-181d:

List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Not in any biclusters.