Searched for:  ELF1

ELF1 mutations modulate:

List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Mutations in ELF1 are not predicted modulate anything in gbmSYGNAL.
 

ELF1 regulates:

List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
RegulatorRegulated Biclusters
ELF129
Regulator (Action)BiclusterSurvival (p-value)Hallmark(s)
ELF1 (Rep.)PITA_612.55 (1.1E-02)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)PITA_1134.92 (8.6E-07)
ELF1 (Rep.)PITA_4132.88 (4.0E-03)Tumor promoting inflammationSelf sufficiency in growth signalsEvading immune detectionInsensitivity to antigrowth signals
ELF1 (Rep.)PITA_5604.49 (7.3E-06)
ELF1 (Rep.)PITA_6072.79 (5.3E-03)
ELF1 (Rep.)TARGETSCAN_603.88 (1.1E-04)
ELF1 (Rep.)TARGETSCAN_852.70 (6.9E-03)
ELF1 (Rep.)TARGETSCAN_1432.78 (5.5E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TARGETSCAN_3813.70 (2.2E-04)
ELF1 (Rep.)TARGETSCAN_3913.41 (6.5E-04)
ELF1 (Rep.)TARGETSCAN_4112.67 (7.5E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TARGETSCAN_4142.92 (3.5E-03)
ELF1 (Rep.)TARGETSCAN_4542.06 (3.9E-02)Self sufficiency in growth signalsTissue invasion and metastasis
ELF1 (Rep.)TARGETSCAN_4563.28 (1.0E-03)
ELF1 (Rep.)TARGETSCAN_5413.29 (1.0E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TARGETSCAN_5762.81 (4.9E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TFBS_DB_1302.45 (1.4E-02)
ELF1 (Rep.)TFBS_DB_1682.53 (1.1E-02)Tumor promoting inflammationSelf sufficiency in growth signalsEvading immune detectionInsensitivity to antigrowth signals
ELF1 (Rep.)TFBS_DB_1813.68 (2.3E-04)
ELF1 (Rep.)TFBS_DB_1862.55 (1.1E-02)Tumor promoting inflammationSelf sufficiency in growth signalsEvading immune detectionInsensitivity to antigrowth signals
ELF1 (Rep.)TFBS_DB_1984.16 (3.2E-05)
ELF1 (Rep.)TFBS_DB_3313.05 (2.3E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TFBS_DB_3732.39 (1.7E-02)
ELF1 (Rep.)TFBS_DB_4012.77 (5.6E-03)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TFBS_DB_4172.35 (1.9E-02)Tumor promoting inflammationEvading immune detection
ELF1 (Rep.)TFBS_DB_4563.85 (1.2E-04)
ELF1 (Rep.)TFBS_DB_5225.01 (5.4E-07)
ELF1 (Rep.)TFBS_DB_5813.25 (1.2E-03)
ELF1 (Rep.)TFBS_DB_163-3.71 (2.1E-04)

Biclusters containing ELF1:

List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Not in any biclusters.