Searched for: hsa-mir-27a
hsa-mir-27a mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Mutations in hsa-mir-27a are not predicted modulate anything in gbmSYGNAL.
hsa-mir-27a regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
| Regulator | Regulated Biclusters |
|---|---|
| hsa-mir-27a | 10 |
| Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
| hsa-mir-27a (Rep.) | TFBS_DB_170 | -2.05 (4.0E-02) | |
| hsa-mir-27a (Rep.) | PITA_251 | -2.34 (1.9E-02) | |
| hsa-mir-27a (Rep.) | PITA_251 | -2.34 (1.9E-02) | |
| hsa-mir-27a (Rep.) | PITA_58 | -2.03 (4.2E-02) | |
| hsa-mir-27a (Rep.) | TFBS_DB_92 | -2.11 (3.5E-02) | |
| hsa-mir-27a (Rep.) | TARGETSCAN_586 | -2.10 (3.5E-02) | |
| hsa-mir-27a (Rep.) | TFBS_DB_6 | -2.53 (1.1E-02) | |
| hsa-mir-27a (Rep.) | PITA_528 | -3.29 (9.9E-04) | |
| hsa-mir-27a (Rep.) | PITA_528 | -3.29 (9.9E-04) | |
| hsa-mir-27a (Rep.) | TARGETSCAN_6 | 2.02 (4.3E-02) | |
| hsa-mir-27a (Rep.) | TARGETSCAN_286 | 0.89 (3.7E-01) |   |
| hsa-mir-27a (Rep.) | TFBS_DB_239 | 1.55 (1.2E-01) | |
Biclusters containing hsa-mir-27a:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Not in any biclusters.