Searched for: hsa-mir-223
hsa-mir-223 mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Mutations in hsa-mir-223 are not predicted modulate anything in gbmSYGNAL.
hsa-mir-223 regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (
Act. = activator and
Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Regulator | Regulated Biclusters |
hsa-mir-223 | 8 |
Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
hsa-mir-223 (Rep.) | PITA_154 | -2.87 (4.1E-03) | |
hsa-mir-223 (Rep.) | PITA_400 | -3.80 (1.5E-04) | |
hsa-mir-223 (Rep.) | TFBS_DB_170 | -2.05 (4.0E-02) | |
hsa-mir-223 (Rep.) | PITA_251 | -2.34 (1.9E-02) | |
hsa-mir-223 (Rep.) | PITA_58 | -2.03 (4.2E-02) | |
hsa-mir-223 (Rep.) | TFBS_DB_92 | -2.11 (3.5E-02) | |
hsa-mir-223 (Rep.) | TARGETSCAN_586 | -2.10 (3.5E-02) | |
hsa-mir-223 (Rep.) | TARGETSCAN_489 | -2.78 (5.5E-03) | |
Biclusters containing hsa-mir-223:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011