Searched for:  TFAP2C

TFAP2C mutations modulate:

List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Mutations in TFAP2C are not predicted modulate anything in gbmSYGNAL.
 

TFAP2C regulates:

List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
RegulatorRegulated Biclusters
TFAP2C11
Regulator (Action)BiclusterSurvival (p-value)Hallmark(s)
TFAP2C (Rep.)PITA_711.98 (4.7E-02)
TFAP2C (Rep.)PITA_1414.69 (2.7E-06)
TFAP2C (Rep.)PITA_1453.88 (1.0E-04)
TFAP2C (Rep.)PITA_2802.54 (1.1E-02)
TFAP2C (Rep.)PITA_3203.25 (1.1E-03)
TFAP2C (Rep.)TARGETSCAN_6022.74 (6.1E-03)
TFAP2C (Rep.)TFBS_DB_122.58 (1.0E-02)
TFAP2C (Rep.)TFBS_DB_1822.78 (5.5E-03)
TFAP2C (Rep.)TFBS_DB_2663.12 (1.8E-03)
TFAP2C (Rep.)TFBS_DB_3513.82 (1.4E-04)
TFAP2C (Rep.)TFBS_DB_426-2.23 (2.6E-02)

Biclusters containing TFAP2C:

List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Not in any biclusters.