Searched for: MYB
MYB mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Mutations in MYB are not predicted modulate anything in gbmSYGNAL.
MYB regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
| Regulator | Regulated Biclusters |
|---|---|
| MYB | 6 |
| Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
| MYB (Rep.) | PITA_133 | 4.22 (2.4E-05) | |
| MYB (Rep.) | PITA_145 | 3.88 (1.0E-04) | |
| MYB (Rep.) | TARGETSCAN_467 | 4.03 (5.5E-05) | |
| MYB (Rep.) | TARGETSCAN_531 | 3.04 (2.3E-03) | |
| MYB (Rep.) | TFBS_DB_122 | 2.85 (4.4E-03) |   |
| MYB (Rep.) | TFBS_DB_180 | 2.28 (2.3E-02) |
Biclusters containing MYB:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Not in any biclusters.