Searched for: CREB3L3
CREB3L3 mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Mutations in CREB3L3 are not predicted modulate anything in gbmSYGNAL.
CREB3L3 regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
| Regulator | Regulated Biclusters |
|---|---|
| CREB3L3 | 4 |
| Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
| CREB3L3 (Rep.) | PITA_320 | 3.25 (1.1E-03) | |
| CREB3L3 (Rep.) | TARGETSCAN_369 | 2.34 (1.9E-02) | |
| CREB3L3 (Rep.) | TARGETSCAN_602 | 2.74 (6.1E-03) | |
| CREB3L3 (Rep.) | TFBS_DB_266 | 3.12 (1.8E-03) |
Biclusters containing CREB3L3:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Not in any biclusters.