Searched for: ZNF281
ZNF281 mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Mutations in ZNF281 are not predicted modulate anything in gbmSYGNAL.
ZNF281 regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
| Regulator | Regulated Biclusters |
|---|---|
| ZNF281 | 8 |
| Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
| ZNF281 (Rep.) | TARGETSCAN_313 | -2.28 (2.3E-02) | |
| ZNF281 (Rep.) | PITA_155 | 4.75 (2.0E-06) | |
| ZNF281 (Rep.) | PITA_462 | 2.45 (1.4E-02) | |
| ZNF281 (Rep.) | TARGETSCAN_571 | 3.50 (4.6E-04) | |
| ZNF281 (Rep.) | TFBS_DB_10 | 2.77 (5.6E-03) | |
| ZNF281 (Rep.) | TFBS_DB_17 | 4.39 (1.1E-05) | |
| ZNF281 (Rep.) | TFBS_DB_43 | 4.00 (6.3E-05) | |
| ZNF281 (Rep.) | TFBS_DB_525 | 2.02 (4.3E-02) |
Biclusters containing ZNF281:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Not in any biclusters.