Searched for:  TEAD2

TEAD2 mutations modulate:

List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Mutations in TEAD2 are not predicted modulate anything in gbmSYGNAL.
 

TEAD2 regulates:

List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
RegulatorRegulated Biclusters
TEAD23
Regulator (Action)BiclusterSurvival (p-value)Hallmark(s)
TEAD2 (Rep.)PITA_2043.31 (9.2E-04)
TEAD2 (Rep.)TARGETSCAN_2860.89 (3.7E-01)Self sufficiency in growth signalsInsensitivity to antigrowth signals
TEAD2 (Rep.)TARGETSCAN_313-2.28 (2.3E-02)

Biclusters containing TEAD2:

List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hallmarks of Cancer
Hanahan and Weinberg, Cell 2011
 

Not in any biclusters.