Searched for: PPARG
PPARG mutations modulate:
List of mutations that drive a causal flow containing a regulator followed by a downstream bicluster. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Mutations in PPARG are not predicted modulate anything in gbmSYGNAL.
PPARG regulates:
List of biclusters regulated by the regulator that was searched. Next to the regulator in parentheses is the regulators mechanism of action (Act. = activator and Rep. = repressor). Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
| Regulator | Regulated Biclusters |
|---|---|
| PPARG | 9 |
| Regulator (Action) | Bicluster | Survival (p-value) | Hallmark(s) |
| PPARG (Rep.) | PITA_229 | 2.48 (1.3E-02) | |
| PPARG (Rep.) | TARGETSCAN_287 | 2.86 (4.2E-03) | |
| PPARG (Rep.) | TARGETSCAN_517 | 3.66 (2.5E-04) | |
| PPARG (Rep.) | TARGETSCAN_541 | 3.29 (1.0E-03) |   |
| PPARG (Rep.) | TARGETSCAN_603 | 2.69 (7.2E-03) | |
| PPARG (Rep.) | TFBS_DB_282 | 3.31 (9.2E-04) | |
| PPARG (Rep.) | TFBS_DB_331 | 3.05 (2.3E-03) | |
| PPARG (Rep.) | TFBS_DB_586 | 4.03 (5.7E-05) | |
| PPARG (Rep.) | TFBS_DB_281 | -2.06 (3.9E-02) |  |
Biclusters containing PPARG:
List of biclusters that contain the genes that was searched. Var. Exp. FPC is the variance explained by the first principal component and is a good measure of bicluster co-expression. Survival is the Cox proportional hazards regression of the bicluster eigengene versus paitent survival. Hallmark(s) is the hallmarks of cancer associated with the bicluster genes. Legend for hallmarks:
Hanahan and Weinberg, Cell 2011
Hanahan and Weinberg, Cell 2011
Not in any biclusters.