|Bicluster Expression of Patient Tumors
Expression of genes from patient tumors in bicluster on left side of red dashed line and out of bicluster on right of red dashed line. Each patient tumor is represented as a boxplot, ordered by their median expression for the bicluster genes (smallest to largest) and colored according to it's GBM subtype.
|Enrichment of Tumor Subtypes in Qunitiles
Patient tumors are sorted as on the left and broken into quintiles following the dashed grey lines. Then each quintile is tested for enrichment of each tumor subtype. The deviation from zero indicate -log10(enrichment p-value), and positive values indicate over-enrichment and negative values underenrichment.
|Genes||Patient Tumors||FPC Var. Exp.|
|Regulators||Causal Flows||Enriched GO BPs||Enriched
Hallmarks of Cancer
|Study||FPC Var. Exp. (Perm. p-value)||Survival (p-value)|
|Gravendeel, et al. 2009|
|Madhavan, et al. 2009|
|Murat, et al. 2008|
|GO Term||GO BP ID||Genes|
Hanahan and Weinberg, Cell 2011